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  • PREVENTIUM 45% Oral Solution Powder
  • PREVENTIUM 45% Oral Solution Powder

PREVENTIUM 45% Oral Solution Powder

  • : (s)
  • : (s) / Month
  • : Medical Products Medicines
  • :
  • :
  • : Turkey
MT SAGLIK URUNLERI A.S.
  • Not Verified
  • Istanbul / Turkey
  • Established 2005
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Description

Tiamulin hydrogen fumarate (or 14-desoxy-14 [(2-diethylamino-ethyl) mercaptoacetoxyj), an active ingredient of 45% Oral Solution Powder, is a semi-synthetically derived pleuromutine group antibiotic. It has bacteriostatic effect by inhibiting protein synthesis of pathogenic mycoplasma and bacteria. The following pathogenic Mycoplasm species are clinically effective against gram-positive and some gram-negative bacteria:

Mycoplasm spp.: Mycoplasma gallisepticum, M. synoviae, M. meleagridis, Ureaplasma spp., M. hyopneumoniae (syn. M. suipneumonia), M. hyorhinis, M. hyosynoviae, M. dispar, M. bovirhinis, M. bovis.

Gram-positive: Clostridium perfringens, Staphylococcus spp., Streptococcus spp., Listeria monocytogenes, Erysipelothrix spp., Corynebacterium pyogenes.

Gram-negative: Pasteurella spp., Klebsiella pneumoniae, Haemophilus spp., Fusobacterium necrophorum, Bacteroides spp., Campylobacter (Vibrio) coli

Treponema: Serpulina (treponema) hyodysenteriae. Leptospira: Leptospira spp.

Pharmacokinetic studies in mammals and poultry have shown that thiamuline is rapidly and almost completely absorbed by oral or injection, followed by classical pharmacokinetic models of clearance of the drug. Following oral administration, it is rapidly absorbed by the gastro-intestinal tract and reaches its maximum blood concentration within 2-4 hours. Following the administration, tiamulin is rapidly transformed into its metabolites that have little or no biological activity within 24 hours. Most of them are excreted in faeces with faeces, and a few in urine.

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